Fact #18: If Left Untreated, It Can Cause Intellectual Disabilities and Growth Delays

Congenital hypothyroidism (CH) is a condition where a newborn’s thyroid gland does not produce enough thyroid hormones, which are essential for brain development, metabolism, and physical growth. If untreated, CH can cause severe Intellectual Disabilities and Growth Delays,.

📌 Fact: Thyroid hormones are crucial for brain development in the first 3 years of life. Without early treatment, congenital hypothyroidism can lead to irreversible brain damage.

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African American baby held in his mother’s arms

🧠 How Does Untreated CH Affect Brain Development?

Thyroid hormones (T3 and T4) play a key role in neural development, learning, and memory formation. Without them, the brain’s ability to form proper connections is severely impaired, leading to:

Severe intellectual disability – Babies may have low IQ, speech delays, and difficulty with problem-solving.
Motor delays – Weak muscle tone, slow reflexes, and poor coordination.
Hearing and speech impairments – Some babies develop deafness or difficulty in speech development.

📌 Fact: Before newborn screening and early treatment, untreated CH was one of the leading causes of preventable intellectual disability worldwide.


📏 How Does CH Affect Physical Growth?

Thyroid hormones are also essential for normal bone growth and metabolism. If left untreated, CH can lead to:

Short stature – Growth failure and delayed bone development.
Slow metabolism – Weight gain, dry skin, and low energy levels.
Delayed puberty – Hormonal imbalances affecting development later in life.

📌 Fact: Children with untreated CH may look much younger than their actual age due to stunted growth.


💊 The Good News: CH Is Treatable!

Daily thyroid hormone replacement (Levothyroxine) can fully prevent intellectual and growth delays.
Early treatment (within the first few weeks of life) leads to normal development.
Lifelong monitoring ensures proper hormone levels for healthy growth.

📌 Fact: With early diagnosis and treatment, babies with congenital hypothyroidism can grow up with normal intelligence and development.


📌 Final Thoughts

If left untreated, congenital hypothyroidism can cause permanent intellectual disabilities and growth delays. However, early detection through newborn screening and lifelong hormone therapy can prevent complications, allowing children with CH to develop normally.

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